President SMIT 2006
Richard M. Satava, MD
DARPA
3701 North Fairfax Drive
Arlington, VA 22203-1714

Scientific Program and
Organization
Andreas Melzer, MD,
Peter Landsberg

University of Applied Sciences
Insite.med
Neidenburgerstrasse 43
D-45877 Gelsenkirchen
Germany

On-Site Management Judy Satava &
Karen S. Morgan
Aligned Management Associates, Inc.
793-A Foothill Blvd., #119
San Luis Obispo CA 93405 www.amainc.com

SMIT Office
Christine Melzer
Fax: +49-208-7402875
E-MAIL: office@smit2006.com

SMIT2006 Conference: Scientific Program (Thursday, May 11th)
Thursday, May 11th Friday, May 12th Saturday, May 13th Sunday, May 14th
Room / Time
Merill Hall
Viewpoint
Surf and Sand
Scripps
08:00 - 18:00 Registration -
Main Lodge Lobby Asilomar
10:00 - 11:30
SMIT SMST Joint Session
Harald Fischer
The V-Crown Aortic Arch Stentgrafts, R. Kaufmann
Intestinal Anastomoses
A Szold Israel
NiTinol in Lap Surgery
D Birkett USA
Innovative use of Nitinol in
Laparoscopic Surgery
Desmond H. Birkett, Department of
General Surgery,
Lahey Clinic Medical Center,
Burlington, MA USA

Nitinol having the unique property of
returning to a preformed shape once a
deformation has been released, or the
deformation can be controlled by
changing the temperature of the metal.
These properties are used to great
effect in laparoscopy where access to
the peritoneal cavity is limited by
narrow straight rigid port placed across
the abdominal wall. As result, Nitinol
becomes an appealing technology that
has a significant future in minimal
access surgery. Her are a few examples
of how it is being used.

The current retrieval bags used for
removing specimens from the
abdominal cavity have Nitinol in the
necks of the bags to open them once
deployed into the peritoneal cavity.
This happens automatically and
permits the easy placement of
specimens into the bags. Nitinol has
been used in retractors which are
introduced straight and once in the
peritoneal cavity form a curve that is
them used to retract intra-abdominal
organs. Most instruments are straight
but Nitinol is used in graspers and
dissectors to deflect them once into
the peritoneal cavity. They are held
straight by a sheath which when pulled
back causes the tip to bend. The
deflection and therefore the angle and
positioning of the tips of the
instrument can be controlled by the
degree to which the rigid sheath of the
instrument is pulled back.

A new and very important use of
Nitinol is effect a bowel anastomosis.
This can be performed as an end to end
or side to side manner using a Nitinol
compression ring. Cooling the Nitinol
ring opens it so that it can be placed
across two ends of tissue. As the ring is
warmed up to body temperature it
closes compressing the bowel together,
holding it together so that it can heal.
The bowel that is compressed by the
ring becomes necrotic, thus freeing the
ring to that it can fall free into the
lumen of the bowel to be passed with
the feces. When performing a
laparoscopic hernia it is often difficult
to unroll the mesh that is being placed
for the repair. Nitinol has been placed
in the edge of the mesh so that as it is
unfolded it automatically opens up.


There are many other potential in the practice of minimal access surgery that
the unique properties of Nitinol can be
used to improve instrumentation.

Intelligent Implants
R Satava USA
Therapeutic Imaging
A Melzer D/UK
From Image Guided Therapy to Therapeutic Imaging
Andreas Melzer, Institute for Medical
Sciences @ Technologies IMS@T,
University of Dundee, Scotland, UK,
andreas@melzer.org

Image-guided therapy has become a
substantially growing area of minimally
invasive procedures. The gold standard
of x ray guided percutaneous
interventions such as biopsies or
catheter based procedures interventions
done in a cathlab is evolving to more
sophisticated image control of devices
for delivery of ablative energy, drugs,
genes to diseased tissues. Advanced
therapeutic imaging will be a core topic
of future medical device development
and clinical research. Thereby non-
ionising radiation based imaging
techniques (US Ultrasound and MRI
magnetic resonance imaging) are key
technologies for guiding and control of
medical devices during interventions
and surgery.

Ultrasound can not only been used for
diagnostic imaging but also to influence
cell membrane interactions, to release
drugs or to destroy tissue. The
applications of MRI guided therapy
using focused ultrasound and other
ablation techniques is unravelled to
navigate to the target lesion and to
monitor temperature responses and
tissue destruction. The links between
clinical diagnosing and treating cancers
through technological innovations
ranging from Sonography to
Sonoporation with US and from
nanoparticle based contrast enhanced
molecular MR imaging to molecular
oncology carry a great potential.
Novel targeted drug delivery using
nanospheres or lysosomes utilizing
heat or electromagnetically activated
drug release in the target volume of a
tumour opens new opportunities for
medical device design.

11:30 - 13:00
LUNCH
SMST Barbeque

Room / Time
Merill Hall
Viewpoint
Surf and Sand
Scripps
Registration -
Main Lodge Lobby Asilomar
14:00 - 15:00
Opening Ceremony
The Ship in a Bottle
J Abele USA
Innovations in Innovation
M Weiner USA
Innovations in Innovations
Mike Weiner, Biophan Inc. West
Henrietta (Rochester) NY, USA

Innovation is often moving along amid
the rocks and shoals of institutional
and financial constraints and barriers,
and not always progressing in the way
we might wish for. Successful
innovations, those which finally make
it through the gauntlet, are proven
effective, and get to market and
widespread utilization, and which,
ideally, bring their inventors and their
champions and organizations fame,
fortune, and recognition, are few and
far between. Society would be much
better off if innovation occurred at a
more rapid pace, and if there were
fewer crashes and failures along the
way, particularly with meritorious
innovations in the life sciences and in
medical devices. Not all of the
meritorious ones survive the journey.
Were there a higher probability, less
risky, less irksome and aggravating, and
a means for innovators to cut a swatch
through the thickets of problems,
obstacles and naysayers, and to get
their innovations to market, this would
be an innovation of great merit and
import. A few selected alternative
paths to innovation and progress are
reported in this presentation, including
several that are the topics of scientific
paper at SMIT2006.

Room / Time
Merill Hall
Viewpoint
Surf and Sand
Scripps
15:00 - 17:00 Set-up for posters and Set up of commercial Exibition in Merill Hall
Special Session TATRC
Gerry Moses
Special Session DARPA
Rick Satava
Hands On Ninitol Devices
Workshop
- H Fischer D
Poster Presentations:
Combat Medic Training
Steve Dawson
Trauma Pod
Pablo Garcia
Training phantoms for MRT / CT / US / Endoscopy, P. Bremer
Improvement of the MR visualisation , E. Immel
Inductive coupled vena cava filter , S. Konak
NASA Extreme Underwater
Tim Broderick
Virtual Autopsy
Craig Mallak
MR inductively coupled active septal Occluder , S. Michitsch
MR compatible cardiovascular simulator , B. Möller
Minimal Access Hysterectomy, Without Laparoscopy , N. Rafla
Percutaneous spine
Tom Mroz
IM-VAC
NN
Artifact exam.of oxidized Nitinol wire in MRI , D. Sachtler
Nanoparticles in MRI ,
D. Sachtler
Conservation system of organs , S. Smajic-Peimann
Future Telesurgery
Mehran Anvari
Virtual Soldier
Brain Athey
Future operating room in Trondheim , B .Ystgaard
Innovations in Surgery
Paul Nagy
LSTAT-lite
Matt Hanson

18:00 - 19:00
Wine Tasting Reception ND&C (Seascape Dining Room Asilomar)
19:00 - 20:00 Opening Dinner (Seascape Dining Room Asilomar)

Thursday, May 11th Friday, May 12th Saturday, May 13th Sunday, May 14th